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When you have cancer, you will probably need lab, imaging, or other tests.

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HER2 human epidermal growth factor receptor 2 is a gene that can play a role in the development of breast cancer. How does this work?

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HER2-positive breast cancers tend to grow faster and are more likely to spread and come back compared to HER2-negative breast cancers. Are these recommendations helpful?

Cancer cells from a tissue sample can be tested to see which genes are normal and abnormal. Breast Cancer Guide.

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For more information on these HER2-targeted therapies, visit the Breastcancer. This is probably because different labs have different rules for classifying positive and negative HER2 status.

In other cases, tissue from one area of a breast cancer can test HER2-positive and tissue from a different area of the cancer can test HER2-negative. Take a quick survey.

Genes contain the recipes for the various proteins a cell needs to stay healthy and function normally. American Society of Clinical Oncology. If a breast cancer is HER2-negative but test classify it as HER2-positive, doctors may recommend anti-HER2 treatment — even though the woman is unlikely to get any benefits and is exposed to the medicines' risks. Was this article helpful?

There are several tests used to find out if breast cancer is HER2-positive. Breast implant illness BII is a term that some women and doctors use to refer to a wide range Subscribe to our podcast for conversations on the issues that matter most. Order a free booklet by mail or download the PDF of the booklet to print it at home.

Your pathology report should include information about HER2 statuswhich tells you whether or not HER2 is playing a role in the cancer. Create a profile for better recommendations.

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July Your Guide to the Breast Cancer Pathology Report is an on-the-go reference booklet you can test out with your doctor or nurse to keep track of the of your pathology report. Each pathologist also may use slightly different criteria to decide whether the are positive or negative. In most cases, this happens when the test are borderline — meaning they aren't strongly HER2-positive or HER2-negative. Inaccurate HER2 test may cause women diagnosed with breast cancer to not get the best neu possible.

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Normally, HER2 receptors help control how a healthy breast cell grows, divides, and repairs itself. American Cancer Society.

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Can we help guide you? It's important to know which HER2 test you had.

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Last modified on September 21, at AM. Some genes and the proteins they make can influence how a breast cancer behaves and how it might respond to a specific treatment. Research has shown that some HER2 status test may be wrong.

How your appear in the report will depend on the test you have. Two of the most common tests are:.

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If all or part of a breast cancer is HER2-positive but test classify it as HER2-negative, doctors aren't likely to recommend anti-HER2 treatment — even though the woman could potentially benefit from those medicines. But there are medicines specifically for HER2-positive breast cancers. The proteins they make can also be tested.

HER2 proteins are receptors on breast cells. This makes breast cells grow and divide in an uncontrolled way.